| Nabil Gabol was born and raised in Lyari, Karachi, Sindh, into the Akhwani clan of the Gabol tribe of the Baloch people in Sindh. |
| His father, Sardar Khan Ahmed Khan Gabol, is a renowned businessman of Lyari. |
| Nabil’s grandfather, Khan Bahadur Allah Bakhsh Gabol, was a politician and served as the first Deputy Speaker of the Sindh Assembly in British India. |
| Nabil's uncle, Barrister Abdul Sattar Gabol, was a close associate of former president and prime minister Zulfikar Ali Bhutto. |
| Nabil joined politics at the age of 24 as a member of the Pakistan People's Party. |
| He served as the youngest Deputy Speaker of the Provincial Assembly of Sindh. |
| In 2016, Nabil announced his support for Imran Khan and his party, Pakistan Tehreek-e-Insaf (PTI). |
| In 2017, Nabil along with his son, Nadir Gabol, re-joined the Pakistan People's Party. |
