| He was born in Burma, which is now known as Myanmar. | 
| Due to political instability in Burma in 1960, his family moved to Rajkot. | 
| His father founded a trading firm named Rasiklal & Sons, and Rupani is a partner in the firm. | 
| Rupani also worked as a stockbroker. | 
| He began his political career as a student activist of Akhil Bhartiya Vidyarthi Parishad (ABVP), the student political wing of BJP. | 
| In 1971, he entered serious politics by joining RSS and Jan Sangh. | 
| During the Emergency in 1976, he spent 11 months in the jails of Bhuj and Bhavnagar. | 
| From 1978 to 1981, he served as a Pracharak of RSS. | 
| In 2006, Rupani was appointed as the Chairman of Gujarat Tourism. | 
| After Vajubhai Vala resigned as the MLA from Rajkot West in August 2014, BJP nominated Vijay Rupani to contest the seat, and he won the by-poll on 9 October 2014. | 
| He became the BJP President of Gujarat on 19 February 2016 and served until August 2016. | 
| As the only cabinet minister to have been jailed during the Emergency, he was part of the Gujarat Government's cabinet in 2016. | 
| After serving as a corporator and Mayor of Rajkot, he became a member of the Rajya Sabha. | 
| He chaired the Manifesto Committee during Keshubhai Patel’s regime. | 
| During Narendra Modi's tenure as Chief Minister of Gujarat, he held the positions of chairman of Gujarat Finance Board and general secretary of BJP’s Gujarat Unit. | 
| In Anandiben Patel’s government, he was the cabinet minister of Transport, water supply, labour, and employment. | 
| Vijay Rupani initiated the Pujit Rupani Memorial Trust for charity in memory of his late son, Pujit. |